What Does Type 2 Diabetes Progression Mean?
Type 2 diabetes happens when your body becomes resistant to insulin. Insulin is a hormone that helps your cells use sugar in the blood (glucose) to make energy. In people with type 2 diabetes, the cells do not respond to insulin properly. As a result, your blood sugar levels rise too high. This can lead to other serious health problems.1
If blood sugar levels are not consistently managed, type 2 diabetes can get worse, or progress, over time. This puts you at higher risk for complications such as:1
- Heart disease
- Nerve damage
- Vision loss
When you are first diagnosed with diabetes, you may be able to manage it through diet and exercise. Over time, however, the condition will progress. Your doctor will likely need to prescribe medicines to help keep your blood sugar in a healthy range. Those medicines may change over time as your body ages.2
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View all responsesWhat is prediabetes?
The first stage of type 2 diabetes is called prediabetes. This means that your blood sugar levels are high but you have not yet progressed to diabetes.3
Prediabetes is a very common condition. And it becomes more common as people age. In fact, about half of people over the age of 65 have prediabetes. About one-third of people under age 65 have prediabetes as well. But most people who have prediabetes do not know they have it. This is because it usually does not cause any symptoms.3
Research shows that some, but not all, people with prediabetes will progress to type 2 diabetes. For example, between 9 and 14 percent of 45-year-olds with prediabetes will develop diabetes within 10 years. Overall, people with prediabetes have a 50-50 chance of developing diabetes within 10 years.3,4
What are the risk factors for prediabetes?
Like diabetes, prediabetes often results from insulin resistance. Insulin resistance can stem from lots of things. These include your genetics, certain medicines, and hormonal disorders.3,4
Other factors that can put you at higher risk of developing prediabetes include:3,4
- Having a parent or sibling with diabetes
- Smoking
- Having an unhealthy body weight (overweight or obesity), especially when fat collects around your midsection
- Exercising fewer than 3 times per week
- Having high blood pressure or abnormal cholesterol levels
- Having a history of diabetes during pregnancy (gestational diabetes)
- Being over age 45
Luckily, prediabetes is reversible for many people. Eating a healthier diet and getting more exercise may be enough to control blood sugar levels. Obesity is a common cause of insulin resistance. So losing weight can help reduce your risk of progression to diabetes.3,4
Also, doctors may prescribe medicines to help prevent prediabetes from progressing. The most common ones are metformin and acarbose.2,3
What are the health risks of type 2 diabetes progression?
If blood sugar levels are not well controlled over time, prediabetes may progress to type 2 diabetes. But diabetes can still be treated at this point. Medicines like metformin, GLP-1 agonists, and insulin can help keep blood sugar levels in a healthy range.1
Unfortunately, these medicines can start to work less well over time. You may need more or different medicines to manage your condition. Experts are not certain why this is, but your genes are likely part of the reason.2
Type 2 diabetes that is not treated effectively can lead to serious health complications, such as:5
- Heart disease
- Chronic kidney disease
- Vision loss or blindness
- Hearing loss
- Nerve damage, often in the feet or hands
- Stroke
Considerations for children
Prediabetes and diabetes in children is a special cause for concern. Type 1 diabetes is still more common than type 2 diabetes among children. But rates of type 2 diabetes are increasing in children and teenagers. Experts think this is a result of increasing rates of childhood obesity.6
Also, some research shows that type 2 diabetes progresses faster in children than in adults. Complications tend to occur more quickly, and medicines have to be changed earlier to prevent them. Researchers are not sure why this is. But they have identified some ways that children’s bodies work differently than adults’ bodies.6
For both children and adults, getting blood sugar levels under control as soon as possible is key to preventing diabetes progression. Faster diabetes progression in children makes early diagnosis and management even more important. If you or your child has any of the risk factors listed above, ask your doctor about diabetes screening.6
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